BDBM118957 US11547697, Compound 9::US9682141, 9

SMILES Nc1ncc2cc(ccc2n1)-c1ccc2nccc(-c3ccncc3)c2c1

InChI Key InChIKey=DDTZPVNPYPIQAT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 118957   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM118957(US11547697, Compound 9 | US9682141, 9)
Affinity DataIC50: <1.00E+3nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF? Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM118957(US11547697, Compound 9 | US9682141, 9)
Affinity DataIC50: >1.00E+4nMAssay Description:The compounds described herein can be tested against recombinant mTOR (Invitrogen) in an assay containing 50 mM HEPES, pH 7.5, 1 mM EGTA, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM118957(US11547697, Compound 9 | US9682141, 9)
Affinity DataIC50: <1.00E+3nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF? Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM118957(US11547697, Compound 9 | US9682141, 9)
Affinity DataIC50: <1.00E+4nMAssay Description:An exemplary system is PI 3-Kinase (human) HTRF? Assay from Upstate. The assay can be carried out according to the procedures suggested by the manufa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent