BDBM11925 9H-fluoren-9-ylmethyl N-[(3S,5S)-5-{[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hexan-2-yl]carbonyl}pyrrolidin-3-yl]carbamate::substituted diprolyl nitrile 18

SMILES O=C(N[C@@H]1CN[C@@H](C1)C(=O)N1[C@H]2C[C@H]2C[C@H]1C#N)OCC1c2ccccc2-c2ccccc12

InChI Key InChIKey=NQAJFLKXOPAIAR-XTFGJOLRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11925   

TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM11925(9H-fluoren-9-ylmethyl N-[(3S,5S)-5-{[(1S,3S,5S)-3-...)
Affinity DataKi:  57nM ΔG°:  -9.78kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed