BDBM11970 (3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[4,3-d][1,3]oxazol-5-yl}-4-(2,5-difluorophenyl)butan-1-one::oxazolopiperidine 72

SMILES N[C@@H](CC(=O)N1CCc2nc(oc2C1)C1CC1)Cc1cc(F)ccc1F

InChI Key InChIKey=PNSBKUPVYFGFQD-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11970   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11970((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[4...)
Affinity DataIC50:  290nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11970((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[4...)
Affinity DataIC50:  3.00E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11970((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[4...)
Affinity DataIC50:  2.80E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11970((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[4...)
Affinity DataIC50:  5.60E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed