BDBM119755 US8685958, 4::US8685958, 5
SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CC(C1)Oc1ccc(CN2CC3(C2)CCCO3)cc1
InChI Key InChIKey=FGJFPWDOUNOKFZ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 119755
Affinity DataIC50: 16nMAssay Description:Melanin Concentrating Hormone Receptor 1 (MCHR1) is a G-protein coupled receptor that interacts with heterotrimeric G proteins containing a Gαi/...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Melanin Concentrating Hormone Receptor 1 (MCHR1) is a G-protein coupled receptor that interacts with heterotrimeric G proteins containing a Gαi/...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair