BDBM119846 US8691986, 12
SMILES CNC(=O)c1ccc(cc1F)-c1nccnc1C1CN(C1)c1ncc2cc(F)c(Cl)cc2n1
InChI Key InChIKey=BTTPLKWZTJDMBV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 119846
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:IMAP TR-FRET progressive binding system, FAM-cAMP substrate were from Molecular Devices (Sunnyvale, Calif.). The PDE IMAP assay was conducted in a 3...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 3.90nMpH: 7.2 T: 2°CAssay Description:IMAP TR-FRET progressive binding system, FAM-cAMP substrate were from Molecular Devices (Sunnyvale, Calif.). The PDE IMAP assay was conducted in a 3...More data for this Ligand-Target Pair