BDBM1199 2-Aminobenzyl-Substituted AHPPA deriv. 14::tert-butyl N-[(2S,3R,4R)-4-{[(4-{[3-(1H-1,3-benzodiazol-2-yl)propanamido]methyl}phenyl)methyl]amino}-4-(benzylcarbamoyl)-3-hydroxy-1-phenylbutan-2-yl]carbamate
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@@H](NCc1ccc(CNC(=O)CCc2nc3ccccc3[nH]2)cc1)C(=O)NCc1ccccc1
InChI Key InChIKey=JANCESINOVSQRO-LVCCDNIOSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 1199
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sandoz Forschungsinstitut Ges.M.B.H.
Curated by ChEMBL
Sandoz Forschungsinstitut Ges.M.B.H.
Curated by ChEMBL
Affinity DataKi: 676nMAssay Description:Inhibitory activity was determined against HIV type 1 proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sandoz Research Institute
Sandoz Research Institute
Affinity DataKi: 680nM ΔG°: -8.75kcal/molepH: 6.25 T: 2°CAssay Description:Enzymatic activity was measured by following cleavage of the substrate H-Lys-Ala-Arg-Val-Leu-pNph-Glu-Ala-Nle-NH2. Products of the cleavage reaction ...More data for this Ligand-Target Pair