BDBM119965 US10738007, Compound B::US11555039, Compound ID B::US8697911, 129
SMILES CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4ccc(cc4)-c4ccncc4)c3)cc2C1
InChI Key InChIKey=FDFPXMUSBROKPG-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 119965
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:The activity of ROCKII (1-543) kinase is measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-luc...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 0.195nMpH: 7.2Assay Description:This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 8.70nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 8.70nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:n general, kinases regulate many important cellular activities including cell growth, signaling, metabolism, etc. Different kinases have distinct fun...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair