BDBM12053 (3S)-3-{[2-(naphthalen-1-yl)benzene]sulfonamido}-4-oxobutanoic acid::(S)-3-(2-Naphthalen-1-yl-benzenesulfonylamino)-4-oxo-butyric acid::arylsulfonamide analogue 17

SMILES OC(=O)C[C@H](NS(=O)(=O)c1ccccc1-c1cccc2ccccc12)C=O

InChI Key InChIKey=GWNHGXUAHVPJPQ-HNNXBMFYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12053   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12053((3S)-3-{[2-(naphthalen-1-yl)benzene]sulfonamido}-4...)
Affinity DataKi:  6.90E+3nM ΔG°:  -7.32kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed