BDBM12066 (3S)-3-({2-[4-(butan-2-yl)-3-methylphenoxy]benzene}sulfonamido)-4-oxobutanoic acid::Diphenyl Ether Sulfonamide 12

SMILES CCC(C)c1ccc(Oc2ccccc2S(=O)(=O)N[C@@H](CC(O)=O)C=O)cc1C

InChI Key InChIKey=TVFTWQDCSBIGAI-WMCAAGNKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12066   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12066((3S)-3-({2-[4-(butan-2-yl)-3-methylphenoxy]benzene...)
Affinity DataKi:  100nM ΔG°:  -9.93kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed