BDBM12068 (3S)-3-{[2-(4-cyclopentylphenoxy)benzene]sulfonamido}-4-oxobutanoic acid::Diphenyl Ether Sulfonamide 14

SMILES OC(=O)C[C@H](NS(=O)(=O)c1ccccc1Oc1ccc(cc1)C1CCCC1)C=O

InChI Key InChIKey=QQWPBGXVOHRBNO-KRWDZBQOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12068   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12068((3S)-3-{[2-(4-cyclopentylphenoxy)benzene]sulfonami...)
Affinity DataKi:  880nM ΔG°:  -8.59kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed