BDBM12092 3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 10::3-N-(2H-1,3-benzodioxole-5-)-5-N-(propan-2-yl)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3,5-dicarboxamide

SMILES CC(C)NC(=O)N1Cc2n[nH]c(NC(=O)c3ccc4OCOc4c3)c2C1

InChI Key InChIKey=IQQAPAMUKYXXIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12092   

TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12092(3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 1...)
Affinity DataIC50:  390nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12092(3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 1...)
Affinity DataIC50:  120nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed