BDBM121444 US8722709, 48

SMILES Cc1cc(F)ccc1CCc1ccnc(NC(N)=O)c1

InChI Key InChIKey=CXKHFDPOIKOCQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 121444   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM121444(US8722709, 48)
Affinity DataIC50:  4.70nMpH: 7.4Assay Description:The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM121444(US8722709, 48)
Affinity DataIC50:  4.70nMAssay Description:Displacement of TAMRA-labeled dexamethasone from full-length human mineralocorticoid receptor expressed in baculovirus infected insect cells after 60...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM121444(US8722709, 48)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at Gal4-fused human MR LBD expressed in HEK293T cells assessed as inhibition of aldosterone-induced transactivation activity afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed