BDBM122640 US8735386, I-110

SMILES COc1cc(ccc1Nc1ncc2CCc3nn(C)c(c3-c2n1)-c1ccccc1Cl)N1CCN(C)CC1

InChI Key InChIKey=VLMVSIQLDXZHRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122640   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122640(US8735386, I-110)
Affinity DataIC50:  0.190nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In DepthDetails US Patent