BDBM12329 5-[(1E)-[(cyclohexylmethoxy)imino]methyl]-6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]pyrimidin-4-amine::oxime analog 18

SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCC3CCCCC3)ccc2[nH]1

InChI Key InChIKey=HCPZISVZYWKEQP-NSKAYECMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12329   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12329(5-[(1E)-[(cyclohexylmethoxy)imino]methyl]-6-[(4-fl...)
Affinity DataIC50:  413nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed