BDBM12334 6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{[2-(morpholin-4-yl)ethoxy]imino}methyl]pyrimidin-4-amine::oxime analog 23

SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCCN3CCOCC3)ccc2[nH]1

InChI Key InChIKey=QZTBTAQOCQKRRB-OPEKNORGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12334   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12334(6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{...)
Affinity DataIC50:  39nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed