BDBM12335 5-[(1E)-{[3-(dimethylamino)propoxy]imino}methyl]-6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]pyrimidin-4-amine::oxime analog 24
SMILES CN(C)CCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F
InChI Key InChIKey=BKDLAIFMKAORSS-YSURURNPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 12335
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
National Tsing Hua University
Curated by ChEMBL
National Tsing Hua University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of RET kinaseMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical
Johnson & Johnson Pharmaceutical
Affinity DataIC50: 101nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair