BDBM12342 2H-chromen-2-one::CHEMBL6466::Coumarin

SMILES O=c1ccc2ccccc2o1

InChI Key InChIKey=ZYGHJZDHTFUPRJ-UHFFFAOYSA-N

Data  56 KI  17 IC50

PDB links: 10 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12342   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM12342(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM12342(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM12342(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 12 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM12342(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 9 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed