BDBM123656 US10562890, Compound 4a::US8748618, AI-4-52

SMILES COc1cccc2[nH]c(nc12)-c1ccccn1

InChI Key InChIKey=CAMACGXEVMSAMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123656   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123656(US10562890, Compound 4a | US8748618, AI-4-52)
Affinity DataIC50: >3.43E+4nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123656(US10562890, Compound 4a | US8748618, AI-4-52)
Affinity DataIC50:  5.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails US Patent