BDBM123656 US10562890, Compound 4a::US8748618, AI-4-52
SMILES COc1cccc2[nH]c(nc12)-c1ccccn1
InChI Key InChIKey=CAMACGXEVMSAMT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 123656
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia Patent Foundation
US Patent
University of Virginia Patent Foundation
US Patent
Affinity DataIC50: >3.43E+4nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation
US Patent
University of Virginia Patent Foundation
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair