BDBM123749 1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (7)

SMILES CCc1ccccc1-n1nc(-c2cccc3ccccc23)c2c(N)ncnc12

InChI Key InChIKey=BGYSWVSWYVKGNS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 123749   

TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  5.20E+3nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  390nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123749(1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...)
Affinity DataIC50:  1.50E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed