BDBM123752 3‐(naphthalen‐1‐yl)‐1‐phenylpyrazolo[3,4‐ d]pyrimidin‐4‐amine (10)::3-(naphthalen-1-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (10)

SMILES Nc1ncnc2n(nc(-c3cccc4ccccc34)c12)-c1ccccc1

InChI Key InChIKey=WBQNNMYOSBMSBZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 123752   

TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)
Affinity DataIC50:  875nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)
Affinity DataIC50:  875nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)
Affinity DataIC50:  545nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123752(3‐(naphthalen‐1‐yl)‐1̴...)
Affinity DataIC50:  675nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed