BDBM12414 CHEMBL27601::benzenesulfonamide::hCA inhibitor, 6

SMILES NS(=O)(=O)c1ccccc1

InChI Key InChIKey=KHBQMWCZKVMBLN-UHFFFAOYSA-N

Data  14 KI  2 IC50  10 Kd

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12414   

TargetCarbonic anhydrase 1/2/5B, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of crude dog red blood cell carbonic anhydraseMore data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant Lp-PLA2 using PED6 as substrate preincubated for 30 mins followed by substrate addition measured for 20 mins by fluor...More data for this Ligand-Target Pair