BDBM125048 US8772511, 5::US9714242, 5
SMILES O=C(NCCc1ccccc1)Nc1ccc2cc(sc2c1)C(=O)N[C@H]1CN2CCC1CC2
InChI Key InChIKey=MORUDEMULGREIK-NRFANRHFSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 125048
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataKi: 22nM ΔG°: -9.70kcal/molepH: 7.4 T: 2°CAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataKi: 22nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMpH: 7.4Assay Description:Membranes from HEK293 cells which express recombinant human 5-HT3 receptor (RB-HS3, Receptor Biology, Inc., MD, USA) are diluted in accordance with t...More data for this Ligand-Target Pair