BDBM125321 US8772480, 140

SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc3[nH]cnc23)C(C)N2CCN(CC2)S(C)(=O)=O)cn1

InChI Key InChIKey=OOZFZHMHOZDAGH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 125321   

LigandPNGBDBM125321(US8772480, 140)
Affinity DataKi:  6nMAssay Description:The PI3K AlphaScreen assay (PerkinElmer, Waltham, Mass.) measures the activity of a panel of four phosphoinositide 3-kinases: PI3Kalpha, PI3Kbeta, PI...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM125321(US8772480, 140)
Affinity DataIC50:  476nMAssay Description:The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent