BDBM126005 US8772282, 1::US8772282, 203

SMILES Cl.NC1=N[C@]2(CN(C[C@H]2CS1)c1ncc(F)cn1)c1ccccc1

InChI Key InChIKey=OUUYOATXWGWJFR-CVHDTDHSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126005   

TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126005(US8772282, 1 | US8772282, 203)
Affinity DataIC50:  64.4nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent