BDBM12881 (5S)-N-[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropyl]-2-oxo-3-phenyloxazolidine-5-carboxamide::(5S)-N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]-2-oxo-3-phenyl-1,3-oxazolidine-5-carboxamide::N-Aryl-oxazolidinone-5-carboxamide Analogue 25a
SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1
InChI Key InChIKey=HVXFNUXEOUIQKE-IARZGTGTSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 12881
Affinity DataKi: 0.525nMAssay Description:Inhibition of HIV1 protease Q7K mutant by FRET methodMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 0.530nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of wild type HIV1 protease by FRETMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of HIV1 protease Q7K mutant by FRET methodMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q498K,D521N,V555I,N579D](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 0.920nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q498K,L501I,G539V,I545V,V555I,V573A](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 2.08nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [491-589,Q498K,L501I,V555I,A562V,G564S,I575V,L581M](Human immunodeficiency virus type 1)
University of Massachusetts Medical School
University of Massachusetts Medical School
Affinity DataKi: 10.3nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair