BDBM12900 (5S)-N-[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl[[(4-trifluoromethoxy)phenyl]sulfonyl]amino]propyl]-2-oxo-3-[(3-trifluoromethyl)phenyl]oxazolidine-5-carboxamide::(5S)-N-[(2S,3R)-3-hydroxy-4-[(2-methylpropyl)[4-(trifluoromethoxy)benzene]sulfonamido]-1-phenylbutan-2-yl]-2-oxo-3-[3-(trifluoromethyl)phenyl]-1,3-oxazolidine-5-carboxamide::N-Aryl-oxazolidinone-5-carboxamide Analogue 28d

SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1cccc(c1)C(F)(F)F)S(=O)(=O)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=YYBURQAPOYNWBT-IARZGTGTSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12900   

TargetDimer of Gag-Pol polyprotein [491-589,Q496K](Human immunodeficiency virus type 1)
University of Massachusetts Medical School

LigandPNGBDBM12900((5S)-N-[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl[[(4...)
Affinity DataKi:  10nMAssay Description:HIV-1 protease inhibitor activities were determined by the fluorescence resonance energy transfer (FRET) method. The energy transfer donor (EDANS) an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed