BDBM130910 US8822500, [4]

SMILES C[C@@H](Cc1c(F)c(F)cc(F)c1F)Nc1cc[nH]c(=O)c1-c1nc2cc3C(=O)N(Cc3cc2[nH]1)C1CCN(C)CC1

InChI Key InChIKey=JNCFIPHVUBZHEG-AWEZNQCLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 130910   

TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130910(US8822500, [4])
Affinity DataIC50:  9.81nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130910(US8822500, [4])
Affinity DataIC50:  5.00nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130910(US8822500, [4])
Affinity DataIC50:  5.98nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130910(US8822500, [4])
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130910(US8822500, [4])
Affinity DataIC50:  0.300nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Chembridge

US Patent
LigandPNGBDBM130910(US8822500, [4])
Affinity DataIC50:  3.48nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails US Patent