BDBM13126 (2R)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-3-methylbutanamide::CGS 27023A Analog 58::CHEMBL85030
SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@H](C(C)C)C(=O)NO
InChI Key InChIKey=ZGSTVUAZFACDLH-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 28 hits for monomerid = 13126
Affinity DataKi: 1.90nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of MMP-13 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of recombinant human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of human active MMP9 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 flu...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human active MMP9 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 flu...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant MMP-1 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human recombinant MMP-3 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of MMP-9 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibitory activity against mouse macrophage metalloelastase (MME) using [3H]elastin as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP-2 (unknown origin) using 7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of MMP-12 (unknown origin)More data for this Ligand-Target Pair