BDBM13190 (2S)-2-amino-N-[4-(4-bromophenyl)-5-phenyl-1,3-thiazol-2-yl]propanamide::SMAC mimetic compound 20g

SMILES C[C@H](N)C(=O)Nc1nc(c(s1)-c1ccccc1)-c1ccc(Br)cc1

InChI Key InChIKey=LETBSEIOGAQYDW-NSHDSACASA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13190   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM13190((2S)-2-amino-N-[4-(4-bromophenyl)-5-phenyl-1,3-thi...)
Affinity DataKd:  750nMAssay Description:Inhibition of XIAP by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13190((2S)-2-amino-N-[4-(4-bromophenyl)-5-phenyl-1,3-thi...)
Affinity DataKd:  740nMAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed