BDBM13219 2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-(2,6-dimethylphenyl)-1,3-thiazole-5-carboxamide::BMS-354825 tert-Butoxycarbamate Analog 5c::CHEMBL129454::tert-butyl N-{5-[(2,6-dimethylphenyl)carbamoyl]-4-methyl-1,3-thiazol-2-yl}carbamate
SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1c(C)cccc1C
InChI Key InChIKey=YKIPORXJATYHIG-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 13219
Affinity DataIC50: 4.40E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of mouse p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair