BDBM132266 US8841312, 8
SMILES C1CCC(C1)n1c2cnccc2c2cnc(Nc3cnc(nc3)N3CCNCC3)nc12
InChI Key InChIKey=PMMUWIAESYJLQU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 132266
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair