BDBM134284 US8853228, F26I
SMILES COc1cc(ccc1C(C)C#Cc1c(C)nc(N)nc1N)-c1c(cccc1C(C)C)C(C)C
InChI Key InChIKey=RUUWASGGNWMBBT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 134284
Affinity DataIC50: 4.20E+3nMAssay Description:Compounds were evaluated in spectrophotometric enzyme assays using ChDHFR-TS and hDHFR. Inhibition constants (IC50) were measured (see Table 4). The ...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
University of Connecticut
US Patent
University of Connecticut
US Patent
Affinity DataIC50: 16nMAssay Description:Compounds were evaluated in spectrophotometric enzyme assays using ChDHFR-TS and hDHFR. Inhibition constants (IC50) were measured (see Table 4). The ...More data for this Ligand-Target Pair