BDBM134505 US8846656, 21-D

SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)cccc1C

InChI Key InChIKey=UPMXCBKERIKIFK-AOYPEHQESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134505   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM134505(US8846656, 21-D)
Affinity DataIC50:  0.5nMAssay Description:Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...More data for this Ligand-Target Pair
In DepthDetails US Patent