BDBM13560 2-[(4-carbamimidoylphenyl)amino]-2-[3-ethyl-5-(oxan-4-yloxy)phenyl]acetic acid::phenylglycine deriv. 8

SMILES CCc1cc(OC2CCOCC2)cc(c1)C(Nc1ccc(cc1)C(N)=N)C(O)=O

InChI Key InChIKey=MYPLUXKPUNFOLX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13560   

TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13560(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethyl-5-(oxa...)
Affinity DataKi:  60nM ΔG°:  -9.75kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13560(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethyl-5-(oxa...)
Affinity DataKi:  1.60E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13560(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethyl-5-(oxa...)
Affinity DataKi:  4.80E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13560(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethyl-5-(oxa...)
Affinity DataKi: >7.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed