BDBM13562 2-[(4-carbamimidoylphenyl)amino]-2-[3-ethynyl-5-(oxan-4-yloxy)phenyl]acetic acid::phenylglycine deriv. 10

SMILES NC(=N)c1ccc(NC(C(O)=O)c2cc(OC3CCOCC3)cc(c2)C#C)cc1

InChI Key InChIKey=ZWQVDURIYFGIDM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13562   

TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13562(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethynyl-5-(o...)
Affinity DataKi:  38nM ΔG°:  -10.0kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13562(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethynyl-5-(o...)
Affinity DataKi:  1.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13562(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethynyl-5-(o...)
Affinity DataKi:  2.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13562(2-[(4-carbamimidoylphenyl)amino]-2-[3-ethynyl-5-(o...)
Affinity DataKi:  4.70E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed