BDBM13564 2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(1-methanesulfonylpiperidin-4-yl)oxy]phenyl}acetic acid::phenylglycine deriv. 12

SMILES CCOc1cc(OC2CCN(CC2)S(C)(=O)=O)cc(c1)C(Nc1ccc(cc1)C(N)=N)C(O)=O

InChI Key InChIKey=MYXDQJCUFNEXCT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13564   

TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13564(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(1...)
Affinity DataKi:  180nM ΔG°:  -9.10kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13564(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(1...)
Affinity DataKi:  3.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13564(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(1...)
Affinity DataKi: >3.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13564(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(1...)
Affinity DataKi:  4.40E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed