BDBM13568 2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(3R)-oxolan-3-yloxy]phenyl}acetic acid::phenylglycine deriv. 16

SMILES CCOc1cc(O[C@@H]2CCOC2)cc(c1)C(Nc1ccc(cc1)C(N)=N)C(O)=O

InChI Key InChIKey=ZKEPSHHZWYCVRH-VTBWFHPJSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13568   

TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13568(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(3...)
Affinity DataKi:  430nM ΔG°:  -8.59kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13568(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(3...)
Affinity DataKi:  9.10E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13568(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(3...)
Affinity DataKi:  9.90E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13568(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(3...)
Affinity DataKi:  1.13E+4nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed