BDBM13570 (2R)-2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-5-[(3S)-oxolan-3-yloxy]phenyl}acetic acid::phenylglycine deriv. 18

SMILES CCOc1cc(O[C@H]2CCOC2)cc(c1)[C@@H](Nc1ccc(cc1)C(N)=N)C(O)=O

InChI Key InChIKey=ZKEPSHHZWYCVRH-QFBILLFUSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13570   

TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13570((2R)-2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-...)
Affinity DataKi:  120nM ΔG°:  -9.34kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13570((2R)-2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-...)
Affinity DataKi:  1.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13570((2R)-2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-...)
Affinity DataKi:  4.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13570((2R)-2-[(4-carbamimidoylphenyl)amino]-2-{3-ethoxy-...)
Affinity DataKi:  4.60E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed