BDBM13580 4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)benzene-1-carboximidamide::benzylamine 6

SMILES COc1cc(CNc2ccc(cc2)C(N)=N)ccc1OCc1ccccc1

InChI Key InChIKey=YPLDWUAEABIXKN-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 13580   

TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  270nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  580nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.10kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  1.20E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMas-related G-protein coupled receptor member X1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataEC50:  510nMAssay Description:Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed