BDBM135801 US8853207, Example-78

SMILES COc1ccc(cc1)-c1n[nH]c-2c1Cc1sc(cc-21)-c1ccc(N)nc1

InChI Key InChIKey=AHORVICCHQDIIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 135801   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM135801(US8853207, Example-78)
Affinity DataIC50:  27.5nMAssay Description:Inhibition of C-kit kinase activity by compounds disclosed herein was quantified by measuring the amount of [33P] incorporated into the substrate in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM135801(US8853207, Example-78)
Affinity DataIC50:  363nMpH: 7.0Assay Description:Inhibition of PDGFR-beta kinase activity by compounds disclosed herein was quantified by measuring the amount of [33P] incorporated into the substrat...More data for this Ligand-Target Pair
In DepthDetails US Patent