BDBM136597 US10005783, 14::US10047097, 14::US10774085, Example 14::US11098046, Compound LOXO-101::US11267818, Example 14::US11453672, Example L-7::US8865698, 14::US9676783, 14

SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F

InChI Key InChIKey=NYNZQNWKBKUAII-KBXCAEBGSA-N

Data  85 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136597   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)
Affinity DataIC50:  140nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed