BDBM136597 US10005783, 14::US10047097, 14::US10774085, Example 14::US11098046, Compound LOXO-101::US11267818, Example 14::US11453672, Example L-7::US8865698, 14::US9676783, 14
SMILES O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
InChI Key InChIKey=NYNZQNWKBKUAII-KBXCAEBGSA-N
Data 85 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 136597
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair