BDBM139203 US8889668, I33

SMILES COc1ccc(F)cc1-c1noc(n1)-c1ccc(c(C)c1)-c1ccccc1C

InChI Key InChIKey=VXALHYHCRPZXOC-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139203   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM139203(US8889668, I33)
Affinity DataKi:  43nM ΔG°:  -9.34kcal/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells wer...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM139203(US8889668, I33)
Affinity DataEC50:  6nMAssay Description:Agonist activity at S1P1 receptor (unknown origin) expressed in CHO cell membranes after 60 mins by [35S] GTPgammaS binding based scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed