BDBM139208 US8889668, I55

SMILES Cc1ccccc1-c1ccc(cc1C(F)(F)F)-c1nc(no1)-c1ccccc1OC(F)(F)F

InChI Key InChIKey=WNSIHSCCQFRORF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139208   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM139208(US8889668, I55)
Affinity DataKi:  8nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells wer...More data for this Ligand-Target Pair
In DepthDetails US Patent