BDBM139468 US8889672, 317-054-001

SMILES CCOC(=O)c1c(N)scc1-c1ccc(OC)cc1F

InChI Key InChIKey=CWECPXDZTSQYHR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139468   

TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM139468(US8889672, 317-054-001)
Affinity DataIC50:  4.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM139468(US8889672, 317-054-001)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM139468(US8889672, 317-054-001)
Affinity DataEC50:  10nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed