BDBM14051 4-(3,4-Dichlorophenyl)-N-1H-indazol-5-yl-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxamide::4-(3,4-dichlorophenyl)-N-(1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxamide::dihydropyridone indazole amide 11
SMILES CC1=C(C(CC(=O)N1)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc2[nH]ncc2c1
InChI Key InChIKey=RHTXWIKPNGROHZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 14051
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP/[gamma-33P] ATP, the subsequent incorporation of 33P into the peptid...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of bovine GRK1 (1 to 535 residues) assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair