BDBM142234 US8933098, 1::US8933099, 1

SMILES Cc1ccc(nc1C(=O)Nc1c(C)cc(cc1C)C(O)=O)N1CCC(O)CC1

InChI Key InChIKey=WOJKYHBOHSQZDW-UHFFFAOYSA-N

Data  8 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 142234   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi:  58nMAssay Description:Binding affinity to human EP4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi:  76nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing human EP1 (Genbank accession number AY275470) or EP4 (Genbank ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi: >1.40E+4nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing human EP1 (Genbank accession number AY275470) or EP4 (Genbank ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi: >1.40E+4nMAssay Description:Binding affinity to human EP3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi: >1.75E+4nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing human EP1 (Genbank accession number AY275470) or EP4 (Genbank ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi: >1.75E+4nMAssay Description:Binding affinity to human EP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi: >1.89E+4nMpH: 7.4Assay Description:hEP1 and hEP4 membranes are prepared from recombinant HEK293 cells stably expressing human EP1 (Genbank accession number AY275470) or EP4 (Genbank ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM142234(US8933098, 1 | US8933099, 1)
Affinity DataKi: >1.89E+4nMAssay Description:Binding affinity to human EP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed