BDBM14300 benzthiazole analog 3::benzyl N-[(2S,4E)-6-amino-1-(1,3-benzothiazol-2-yl)-1-oxohex-4-en-2-yl]carbamate

SMILES NCCCCC(=NC(=O)OCc1ccccc1)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=NMLVAPSCVXROFT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14300   

TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14300(benzthiazole analog 3 | benzyl N-[(2S,4E)-6-amino-...)
Affinity DataKi:  2.80E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14300(benzthiazole analog 3 | benzyl N-[(2S,4E)-6-amino-...)
Affinity DataKi:  2.50E+4nM ΔG°:  -6.21kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed