BDBM143130 US9682953, 2.A-1
SMILES FC(F)(F)c1ccc(Oc2cccc(C=C3CCC(CC3)NC(=O)c3cc[nH]n3)c2)nc1
InChI Key InChIKey=FAGGWGJTJJMQQE-QINSGFPZSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 143130
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human transmembrane domain deficient FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mi...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Advinus Therapeutics
Curated by ChEMBL
Advinus Therapeutics
Curated by ChEMBL
Affinity DataIC50: 266nMAssay Description:Inhibition of rat FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Advinus Therapeutics
Curated by ChEMBL
Advinus Therapeutics
Curated by ChEMBL
Affinity DataIC50: 418nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair