BDBM14319 1-methyl-1H-1,3-benzodiazol-2-amine::Fragment 16

SMILES Cn1c(N)nc2ccccc12

InChI Key InChIKey=XDFZKQJLNGNJAN-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14319   

TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14319(1-methyl-1H-1,3-benzodiazol-2-amine | Fragment 16)
Affinity DataKi:  3.70E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14319(1-methyl-1H-1,3-benzodiazol-2-amine | Fragment 16)
Affinity DataKi:  1.80E+6nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Rattus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM14319(1-methyl-1H-1,3-benzodiazol-2-amine | Fragment 16)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM14319(1-methyl-1H-1,3-benzodiazol-2-amine | Fragment 16)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed