BDBM143291 US9682953, 2.E-27

SMILES Cc1nc(Oc2cccc(C=C3CCC(CC3)NC(=O)c3cnc(N)nc3)c2)ccc1Cl

InChI Key InChIKey=RHYXISNBTHRNLT-WJDWOHSUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143291   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Advinus Therapeutics

US Patent
LigandPNGBDBM143291(US9682953, 2.E-27)
Affinity DataIC50:  17nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM143291(US9682953, 2.E-27)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent